Homocysteine and Its Effects in Alzheimer’s and Epilepsy

  • KRISHAN RAJ SINGH

Abstract

This report covers the basis and a brief study related to homocysteine and neurological disorders caused by homocysteine. Homocysteine is basically a type of amino acid found in the human blood. An abnormal state of homocysteine in blood causes endothelial cell damage in humans, which causes several issues in the body such as irritation in veins and atherogenesis which ultimately cause ischemic diseases. Hyperhomocysteinemia is subsequently a conceivable hazard factor for coronary supply route ailment. This report also includes the information related to various neurological disorders related to homocysteine, such as Alzheimer’s and epilepsy. There are various treatments and diagnosis also related to such disease caused by homocysteinemia. Stroke and Alzheimer's disease (AD) frequently occur together. Hyperhomocysteinaemia was linked to both histologically proven AD and disease progression in epidemiological investigations, and dementia in AD was linked to postmortem evidence of brain infarctions. Hyperhomocysteinemia and Alzheimer's disease may thus be connected via stroke or microvascular illness. Direct causative pathways are also possible, given the established links between B-group vitamin insufficiency and both hyperhomocysteinaemia and neurological impairment.