A Review Paper on Drug Delivery Approaches

Abstract

Various approaches to drug delivery can be used to optimise therapeutic effectiveness and reduce side effects by influencing a drug compound's absorption, dissemination, metabolism, and removal (ADME). Techniques such as amorphous solid dispersion, liposomes, and complexion have been used to enhance their oral bioavailability for certain medications with poor water solubility or low permeability. Modified release (MR) formulations have been widely used to improve patient compliance and to minimise side effects, especially for short half-lives or small therapeutic windows of medicines. More than ten medications have been successfully marketed using sterile long-acting release (LAR) formulations with strong clinical benefit. In addition, drug delivery devices have been used in slowing procedures for drug approval. In addition, the modification of the distribution of in vivo drugs using selective delivery systems has greatly enhanced oncology therapies. Many of the methods to drug distribution have their benefits and drawbacks. Achieving consistent consistency and clinical performance using drug delivery systems can also pose significant challenges for both branded and generic drugs in creating a drug for the market, requiring close cooperation between industry, academia and regulatory agencies. With the introduction of personalized drugs, the use of drug delivery technologies to provide improved goods and services for patients would present great opportunities and challenges.