Review on Lung Cancer and Apoptosis

Abstract

The molecular events that lead to drug-induced apoptosis are necessary to understand, and how

Apoptotic death evades tumours. In both tumorigenesis and drug resistance, defects in apoptosis are involved, and these Chemotherapy failures are caused by defects. These studies should clarify the relationship between the genetics of cancer and sensitivity to medication, which should allow a more realistic approach to the design and therapy of anticancer drugs. Cancer of the lung is the leading cause of cancer deaths worldwide. Small cell lung carcinoma (SCLC) and lung carcinoma of non-small cells the two key types of lung cancer that vary in their susceptibility to apoptosis are (NSCLC). The role is played by control of apoptosis in lung cancer is examined with a significant focus on the differential sensitivities of the major subtypes.