In vitro antibacterial and phytochemical analysis of cassia fistula against bacteria isolated from diarrheal samples
Abstract
Various medicinal plant species are moving from fringe to mainstream and being used by a large numbers of people who are seeking remedies and health approaches from natural products. Cassia fistula is well known for its wealth of antimicrobial metabolites and medicinal property. In present study, three bacteria were isolated from diarrheal patients samples and leaves of C. fistula were screened in-vitro for antimicrobial activity and presence of important phytochemicals. This study was carried out with an objective to investigate the antibacterial activity of Cassia fistula Linn. The aim of the study is to assess the antimicrobial activity and to determine the zone of inhibition of extracts on some bacterial strains. The antibacterial activities of extracts of Cassia fistula was tested against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa .The results showed that the remarkable inhibition of the bacterial growth was shown against the tested organisms. The microbial activity of the Cassia fistula was due to the presence of various secondary metabolites2. The results revealed that the possible presence of alkaloids, phenolics and tannins, flavonoids, carbohydrates and glycosides, terpenoids. Hence, these plants can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.